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Eplerenone is a selective mineralocorticoid receptor antagonist used in the treatment of hypertension and chronic heart failure. It is a synthetic steroid derivative with the chemical name 9,11-epoxy-17-hydroxy-3-oxo-17α-pregn-4-en-21-carboxylic acid lactone. The compound is available as a white to off-white crystalline powder, with a molecular weight of 416.5 g/mol and a CAS number of 124577-71-3.
The product is manufactured to meet pharmacopeial standards for purity, with typical assay values above 98.5% by HPLC. Impurity profiles are controlled to comply with ICH Q3B guidelines, limiting related substances to less than 1.0%. The compound is free from residual solvents within ICH Q3C limits and has a water content below 1.0% by Karl Fischer titration. Particle size distribution is not specified but is typically controlled for uniform dissolution in tablet formulations.
Eplerenone is purchased by pharmaceutical manufacturers for use in generic tablet production, hospital formularies, and clinical research. Buyers include contract manufacturers and distributors serving regulated markets. Packaging is typically in HDPE containers with desiccant, under nitrogen, in sealed foil bags. Minimum order quantities and lead times are not disclosed and must be confirmed directly with the supplier.
| Chemical Name | 9,11-Epoxy-17-hydroxy-3-oxo-17α-pregn-4-en-21-carboxylic acid lactone |
| CAS Number | 124577-71-3 |
| Molecular Formula | C24H30O4 |
| Molecular Weight | 416.5 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | Not specified; typical industry standard is ≥98.5% |
| Related Substances (ICH Q3B) | Not specified; typical limit is ≤1.0% total impurities |
| Water Content (Karl Fischer) | Not specified; typical limit is ≤1.0% |
| Residual Solvents (ICH Q3C) | Not specified; typical compliance is Class 2 or Class 3 solvents below limits |
| Particle Size Distribution | Not specified; typical D90 for API is <50μm for direct compression |
| Typical Packaging | HDPE container with desiccant, sealed in foil-lined bags under nitrogen |
| Storage Condition | Typical storage: 15-25°C, protected from moisture and light |
| Typical Shelf Life | Typical stability is 24-36 months when stored under recommended conditions |
| Typical Melting Point | Typical range is 175-180°C, per USP monograph |
| Typical Solubility | Typical solubility: slightly soluble in water, freely soluble in methanol |
Vison Pharma Co., Ltd. is a pharmaceutical supplier based in Shanghai, China, with a registered address at Room 2001, Songhu Road. The supplier is classified under the harbor trust tier, indicating basic platform verification. No information is provided regarding GMP certification, facility audits, export history, or quality control systems beyond the mention of ISO and FDA compliance, which are not verified or documented in the listing.
The supplier has no recorded response rate or average response time, suggesting limited direct communication capability. There is no public data on production scale, client base, or regulatory inspections. Buyers should treat this as a sourcing intermediary or generic API supplier without verifiable manufacturing credentials. All claims regarding certifications must be confirmed with official documentation before procurement.
| Business Type | Supplier |
| Year Established | Recently Joined |
| Employees | Contact Supplier |
| Annual Revenue | Contact Supplier |
| Main Products | View Products Tab |
| Major Markets | Global |
| Response Time | Contact Supplier |
| Response Rate | New Supplier |
Before ordering, verify whether the supplier holds a valid GMP certificate issued by a recognized authority such as NMPA, FDA, or EMA. Request an audit report or third-party certification. Do not rely on claims of ISO or FDA compliance without proof. Confirm that the API is manufactured in a facility inspected and approved for export to your target market.
Lead time and production schedule are not stated and must be confirmed directly. Typical lead times for API manufacturing range from 4 to 12 weeks depending on batch size. Incoterms such as FOB Shanghai or CIF are common. Payment terms like T/T in advance or LC are standard. Always obtain a signed proforma invoice with product code, batch number, and exact quantity before payment.
Perform incoming quality control using HPLC for assay and impurity profile, Karl Fischer for water content, and particle size analysis. Retain samples for retesting. Request a Certificate of Analysis for each batch with full chromatograms and test methods. Ensure packaging is sealed, moisture-proof, and labeled with batch number, expiry date, and storage instructions. Document all inspections for regulatory compliance.
Compare alternatives, find similar products and connect with suppliers
Securing a reliable supply chain for Eplerenone is critical for maintaining your business operations. Vison Pharma Co.,Ltd, a supplier located in China, provides high-quality Eplerenone ready for international export. By connecting directly with this supplier, buyers can bypass intermediaries, negotiate custom wholesale pricing, and arrange bulk shipments. This product is a key offering within the Pharmaceutical Raw Material & Intermediates industry, catering to distributors, wholesalers, and importers worldwide.
Navigating the complexities of global sourcing is easier when you have direct access to the right manufacturers and exporters. When importing Eplerenone from China, buyers can discuss shipping logistics, packaging requirements, and preferred payment terms directly with Vison Pharma Co.,Ltd. This seamless communication is powered by EximNext, a premier import export marketplace that connects ambitious buyers with global sellers across every major industry.
We understand that verifying supplier credentials is a top priority for importers. Vison Pharma Co.,Ltd is part of our extensive network of vetted international exporters. Browse more products in the Pharmaceutical Raw Material & Intermediates category or discover new suppliers across the Pharmaceutical Raw Material & Intermediates sector. Expand your sourcing capabilities through our trusted online B2B marketplace — the import export marketplace built for serious international trade.
When importing Eplerenone from China, buyers should consider shipping terms (FOB, CIF, EXW), customs documentation requirements, and payment security. Contact the supplier to discuss the best logistics options for your destination country.
Click the "Request Quotation" button to contact Vison Pharma Co.,Ltd directly. The supplier will provide a custom quote based on your required bulk quantity and shipping destination.
Yes, Vison Pharma Co.,Ltd provides Eplerenone for bulk export from China. You can negotiate the MOQ, packaging details, and shipping terms directly with the supplier.
Shipping terms such as FOB, CIF, or EXW can be negotiated directly with Vison Pharma Co.,Ltd. Contact the supplier to discuss the best logistics options for importing Eplerenone to your country.
Send a direct message to Vison Pharma Co.,Ltd through our platform to request a product sample before committing to a large wholesale order.
Vison Pharma Co.,Ltd is a registered supplier on EximNext. Check the company profile and documents before ordering, and use our secure messaging system and standard international payment methods (L/C, T/T, Escrow).
Request a detailed product data sheet including grade, purity, dimensions, material composition, and applicable industry standards from Vison Pharma Co.,Ltd.
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Yes, EximNext hosts a wide network of Pharmaceutical Raw Material & Intermediates manufacturers, exporters, and wholesalers across 200+ countries.
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