Import Bmp-4 — Buy in wholesale FOB from Supplier in India

BMP-4 Recombinant Protein (Catalog ESM12248-3) is a mouse host-derived, human-reactive growth factor cytokine supplied in a 60L volume format, validated for immunocytochemistry, immunofluorescence, and flow cytometry applications. This reagent targets Bone Morphogenetic Protein-4, a morphogen critical to mesoderm patterning, limb bud development, and stem cell differentiation protocols. The unit price is 28,350 INR for the 60L presentation, positioning it within research-grade reagent pricing for developmental biology and regenerative medicine programmes requiring defined bioactive protein.

The recombinant production in mouse host systems yields a defined protein product distinct from native extraction methods, with human reactivity confirmed across ICC/IF, IF, and FCM assay formats. Researchers should note that BMP-4 signalling potency varies significantly with protein folding state and glycosylation pattern, factors influenced by expression system and purification protocol. The listing does not specify whether this preparation represents the mature active dimer, pro-domain containing precursor, or a tagged fusion construct, each of which exhibits different biological activity profiles in embryoid body differentiation and mesenchymal stem cell osteogenesis assays.

Primary application areas include developmental biology laboratories studying dorsoventral axis specification, pharmaceutical groups developing bone anabolic therapies, and clinical research institutions investigating congenital malformations. The inclusion of flow cytometry among validated applications distinguishes this reagent from the BMP-2 antibody, suggesting surface staining or intracellular detection capability for cell sorting workflows. International buyers should verify protein stability data under shipping conditions and confirm that endotoxin levels meet their cell culture or in vivo application thresholds, as these specifications are not stated in the source material.

Origin Diagnostics & Research operates from Clappana, Karunagappally, Kollam, Kerala 690525, India, a location in the Kollam district of southwestern India with developing logistics connectivity for temperature-sensitive biological exports. The supplier's trust tier is Harbor, representing entry-level platform verification without enhanced accreditation. The zero percent response rate and zero recorded average response hours indicate potential communication delays, suggesting buyers may need to engage through multiple contact attempts or consider agent-assisted procurement for time-sensitive orders.

The company's offering spans recombinant cytokines and antibody reagents for research markets, with this BMP-4 protein complementing their BMP-2 antibody line. No ISO certification, GMP compliance statement, manufacturing scale, employee count, annual revenue, or named reference customers appear in the available profile. Buyers should independently assess manufacturing reproducibility, batch-to-batch coefficient of variation in bioactivity assays, and technical support responsiveness before establishing this supplier as a critical reagent source for multi-year research programmes.