Import Bcl-Xl / Bcl2l1 — Buy in wholesale FOB from Supplier in India

The Bcl-XL / BCL2L1 reagent is a mouse monoclonal antibody directed against the human BCL2L1 gene product, supplied by Origin Diagnostics & Research from their facility in Kollam, Kerala, India. The clone is preserved in solution format at 60L volume per unit, designed for quantitative detection of BCL2L1 protein expression. The host species is mouse, with confirmed reactivity against human (H) antigen. Validated applications include ELISA (enzyme-linked immunosorbent assay) and flow cytometry (FCM), positioning it for apoptosis pathway analysis, oncology biomarker research, and drug discovery screening programmes. The catalogue number ESM12202-3 identifies this specific formulation.

The antibody belongs to the Bcl-2 family of regulators, where Bcl-XL functions as an key anti-apoptotic protein by inhibiting cytochrome c release from mitochondria. In research contexts, monoclonal antibodies against this target require high specificity to distinguish Bcl-XL from closely related family members (Bcl-2, Mcl-1, Bcl-w, Bcl-B). The preserved solution format indicates ready-to-use dilution rather than lyophilised powder, with typical mouse monoclonal preservatives including sodium azide or proprietary stabilisers. The exact immunogen sequence, clone identifier, and epitope mapping are not stated in source data. Isotype subclass (IgG1, IgG2a, IgG2b, or IgM) and light chain type (kappa or lambda) require supplier confirmation.

Typical buyers include pharmaceutical companies conducting high-throughput screening, academic medical centres investigating apoptotic mechanisms in cancer, and contract research organisations supporting drug development. The 60L volume format suggests bulk screening capability rather than small-scale analytical use. Researchers should confirm lot-to-lot consistency data, certificate of analysis parameters, and whether the antibody has been tested in additional applications (Western blot, immunohistochemistry, immunoprecipitation, functional neutralisation) beyond the stated ELISA and flow cytometry validation. Cold chain requirements, shelf life, and stability data are essential procurement considerations not provided in the source.

Origin Diagnostics & Research operates from Clappana, Karunagappally, Kollam 690525, Kerala, India. Kollam district lies along the Malabar Coast with emerging biotechnology and diagnostic reagent activity, though it is not among India's primary biotech clusters (Bengaluru, Hyderabad, Pune). The supplier holds a 'harbor' trust tier with zero recorded response rate and no average response hours, indicating limited transaction history visibility through this channel. The address format suggests a single-location operation rather than multiple facility network. No information is provided regarding GLP, GMP, or ISO 13485 quality management certification.

The source description positions the company as serving research applications with this specific antibody reagent, but provides no data on establishment year, scientific staff qualifications, production capacity, or whether manufacturing occurs in-house or through contract manufacturing organisations. There is no mention of international distributor relationships, prior publications citing their reagents, or participation in external quality assurance programmes (such as NordiQC or UK NEQAS equivalents). Buyers should request a company profile, quality manual, and references from peer institutions before committing to volume orders. The India origin may offer cost advantages, but buyers in regulated markets should verify export documentation capability and customs HS classification familiarity.