About Shangdong Kangnuo Bioengineering Co., Ltd - Chemicals & Allied Products Supplier in China

China is the origin country for Shangdong Kangnuo Bioengineering Co., Ltd, which lists six active pharmaceutical ingredients in its catalogue. The portfolio comprises the ACE‑inhibitors Lisinopril, Quinapril hydrochloride, Fosinopril sodium and Perindopril, the beta‑blocker Carvedilol, and the antidepressant Amfebutamone hydrochloride. Perindopril is recorded with HS code 2937.29 and described as Perindopril Erbumine / Arginine Salt, Pharmaceutical Grade. Amfebutamone hydrochloride is recorded with HS code 2934.99 and specified as the hydrochloride salt of C13H18ClNO‑HCl. All six items are classified under the Chemicals & Allied Products category used in customs and trade data.

The four remaining compounds - Lisinopril, Quinapril hydrochloride, Fosinopril sodium and Carvedilol - are listed without explicit HS codes but fall within HS chapter 29 for organic chemicals and pharmaceutical intermediates. The supplier is designated as an imported tier with a harbor trust tier, indicating it operates through third‑party logistics for cross‑border shipments. Each active ingredient is supplied in bulk pharmaceutical grade, suitable for further formulation into tablets, capsules or injectables. The catalogue does not disclose packaging dimensions, but bulk API shipments from China are commonly packed in 25 kg drums or 1 ton IBC containers. The six listed products represent the full active product count reported for this supplier.

Product Range and Specialties of Shangdong Kangnuo Bioengineering Co., Ltd

Shangdong Kangnuo Bioengineering’s catalogue lists six active pharmaceutical ingredients: Lisinopril, Quinapril hydrochloride, Fosinopril sodium, Carvedilol, Perindopril (HS 2937.29, Perindopril Erbumine/Arginine Salt) and Amfebutamone hydrochloride (HS 2934.99, C13H18ClNO‑HCl). In the global API market these molecules are typically supplied with a minimum assay of 99 % and impurity limits defined by USP‑NF or EP monographs. Perindopril and the other ACE inhibitors are often sold as free‑base or salt forms, with particle size distributions between 50 µm and 200 µm for optimal tableting. Carvedilol is commonly offered as a racemic mixture with a moisture content below 0.5 % and a bulk density around 0.45 g/cm³. Amfebutamone hydrochloride, known as bupropion HCl, is usually provided with a purity of ≥99.5 % and a residual solvent profile meeting ICH Q3C limits. Buyers generally request certificates of analysis, stability data and compliance with GMP or ISO 9001 for these API grades.

Trade and Export Information - Shangdong Kangnuo Bioengineering Co., Ltd

China is one of the world’s largest exporters of pharmaceutical active ingredients, and shipments from Chinese manufacturers are routinely directed to North America, the European Union, and emerging markets in Asia‑Pacific. The HS codes 2937.29 for Perindopril and 2934.99 for Amfebutamone hydrochloride belong to Chapter 29, which covers organic chemicals, and customs authorities often require a detailed product description and a certificate of origin for these codes. Importing companies typically request GMP certification, a certificate of analysis, and, where applicable, WHO pre‑qualification or FDA‑recognized facility status. Bulk API exports are packed in 25 kg drums, 500 kg IBCs, or 20‑ft containers, with UN 3373 labeling for hazardous substances when required. Common Incoterms used for Chinese API shipments include FOB Shanghai or CIF Hong Kong, allowing buyers to arrange customs clearance in the destination country. Regulatory agencies in the destination market may also demand a drug master file (DMF) or an active pharmaceutical ingredient (API) dossier that references the supplier’s manufacturing process. Buyers of ACE‑inhibitors and beta‑blockers frequently operate in cardiovascular drug manufacturing, while Amfebutamone hydrochloride serves the antidepressant and smoking‑cessation sectors. These industries often require compliance with ICH Q7 for API manufacturing and may conduct third‑party audits before contract manufacturing. Chinese API exporters also benefit from the country’s established logistics corridors, with major ports such as Shanghai, Shenzhen and Tianjin handling the majority of pharmaceutical cargo.

Sourcing from Shangdong Kangnuo Bioengineering Co., Ltd - Buyer Guidance

When sourcing the six APIs from Shangdong Kangnuo Bioengineering, buyers should request a current GMP certificate and, if available, ISO 9001 or ISO 13485 certification to verify the manufacturing system. A detailed certificate of analysis for each batch, including assay, related substances, heavy metals, residual solvents and microbial limits, is essential for regulatory compliance. Samples of the bulk powder, typically supplied in 500 g sealed containers, allow verification of particle size, moisture content and dissolution profile before full‑scale purchase. Buyers should confirm that the HS codes disclosed (2937.29 for Perindopril and 2934.99 for Amfebutamone hydrochloride) match the invoice and packing list to avoid customs delays. Typical minimum order quantities for bulk API range from 5 kg to 20 kg per compound, with lead times of 30‑45 days after order confirmation, subject to raw material availability. It is prudent to arrange an independent third‑party inspection or laboratory testing of the initial shipment to ensure that purity and impurity specifications meet USP‑NF or EP standards.

What types of products does Shangdong Kangnuo Bioengineering offer?

The supplier lists six active pharmaceutical ingredients: Lisinopril, Quinapril hydrochloride, Fosinopril sodium, Carvedilol, Perindopril (HS 2937.29) and Amfebutamone hydrochloride (HS 2934.99). All items fall under the Chemicals & Allied Products category.

Which HS codes are associated with the supplier’s catalogue?

Perindopril is assigned HS code 2937.29 and Amfebutamone hydrochloride carries HS code 2934.99. The other four APIs are categorized within HS chapter 29 for organic chemicals, though specific codes are not listed in the catalogue.

What certifications should a buyer request from this supplier?

Buyers should request a current GMP certificate and, where possible, ISO 9001 or ISO 13485 certification. Additional documentation such as a certificate of analysis for each batch is standard for pharmaceutical APIs.

How are the APIs typically packaged for export?

Chinese API exporters commonly use 25 kg steel drums, 500 kg intermediate bulk containers (IBCs), or bulk shipments in 20‑ft containers. Small sample quantities are often supplied in sealed 500 g polyethylene bags.

What are the usual minimum order quantities and lead times?

Minimum order quantities usually range from 5 kg to 20 kg per active ingredient. Lead times reported by similar Chinese API manufacturers are typically 30‑45 days after order confirmation, depending on raw material availability.

How can a buyer obtain a sample for quality verification?

Buyers can request a 500 g sample sealed in a tamper‑evident bag, accompanied by a certificate of analysis that details assay, impurity profile and physical properties such as particle size and moisture content.

Which regions commonly import these APIs from China?

The primary import regions for Chinese pharmaceutical APIs are North America, the European Union, and Asia‑Pacific countries such as Japan, South Korea and Australia. These markets often require GMP compliance and detailed regulatory dossiers.

What documentation is needed for customs clearance of these products?

Customs clearance typically requires a commercial invoice, packing list, certificate of origin, and the appropriate HS code declaration. For pharmaceutical APIs, a certificate of analysis and evidence of GMP compliance are frequently requested by the importing country’s regulatory authority.