Cbz-l-valine

Cbz-l-valine is a protected amino acid derivative used as a building block in peptide synthesis and biochemical research. This product is a carbobenzyloxy (Cbz) protected form of l-valine, offering selective protection for the amine group while preserving the chiral integrity of the valine residue. The compound is supplied as a fine white to off-white crystalline powder with a typical purity of 98% or higher, suitable for laboratory and industrial applications where precise amino acid modification is required.

The Cbz protecting group is stable under neutral and basic conditions but can be removed via hydrogenolysis or mild acid treatment, making it a versatile choice for orthogonal protection strategies. L-valine itself is a branched-chain amino acid, and its Cbz-protected form retains the hydrophobic side chain, which is critical for maintaining the structural and functional properties of the final peptide. Standard industry specifications for such derivatives include a melting point range of 80-85°C, a specific rotation of +20 to +25° (c=1, methanol), and minimal residual solvents as per ICH guidelines.

This derivative is primarily used in the pharmaceutical and biotechnology sectors for the synthesis of therapeutic peptides, research reagents, and diagnostic kits. Buyers typically include contract manufacturing organisations, research institutions, and specialty chemical producers. The product is shipped in sealed containers under controlled conditions to prevent moisture absorption and degradation. Confirm packaging, storage recommendations, and any specific handling requirements with the supplier before ordering.

Ningbo Create Biological Project Co., Ltd is based in Genyu Rd., Guisi Industry Zone, Ningbo, Zhenhai, China. The company operates as an imported-tier supplier with a harbor trust classification, indicating a baseline level of verification for international trade. The supplier’s profile does not specify a response rate or average response time, so buyers should anticipate potential delays in communication and plan accordingly.

The company specialises in biochemical products, including amino acid derivatives like Cbz-l-valine. While the profile does not detail certifications, production capacity, or client history, its focus on niche chemical intermediates suggests a targeted expertise. Buyers are advised to directly request documentation on quality control processes, batch consistency, and compliance with relevant pharmaceutical or biotech standards before finalising any purchase.