Import Boc-D-Arg(Tos)-Oh Etoac — Buy in wholesale FOB from Supplier in China

Boc-d-arg(tos)-oh Etoac is a protected D-arginine derivative with molecular formula C18H28N4O6S and molecular weight 428.51 g/mol, supplied by Wuhan Yuan Cheng GongChuang Technology Co.Ltd from Wuhan, Hubei Province, China. The compound features N-alpha-Boc (tert-butyloxycarbonyl) protection, N-omega-tosyl (4-toluenesulfonyl) protection on the guanidinium side chain, and an ethyl ester moiety, making it a specifically configured intermediate for solid-phase and solution-phase peptide synthesis. The material is supplied in bulk packaging (25kg/drum standard) with a stated assay of 99% for pharmaceutical and biotechnology manufacturing applications.

The Boc protecting group provides acid-labile amine protection removable with trifluoroacetic acid, while the tosyl group on the guanidinium functionality requires stronger conditions (typically HF or TFMSA in peptide synthesis contexts) for deprotection. This orthogonal protection strategy is standard for arginine residues in classical peptide synthesis protocols before the widespread adoption of Fmoc-based methodologies. The ethyl ester form provides a carboxy-protected intermediate that can be selectively hydrolysed or used directly in coupling reactions depending on synthetic route. Storage requirements are strict due to the reactivity of the protected amino acid, hygroscopicity of the salt form, and potential for degradation under humid or warm conditions.

Primary buyers include custom peptide synthesis houses, generic API manufacturers, and biotechnology companies constructing arginine-containing therapeutic peptides. The compound serves as a building block for peptides requiring D-arginine chirality, which confers distinct pharmacokinetic properties including altered protease resistance and receptor binding profiles compared to L-arginine analogues. Buyers should confirm current GMP status, DMF availability, and specific impurity profiles (including diastereomeric purity and residual solvent specifications) directly with Wuhan Yuan Cheng GongChuang Technology Co.Ltd, as these critical pharmaceutical quality parameters are not stated in the source data.

Wuhan Yuan Cheng GongChuang Technology Co.Ltd is located in Qianjiajie, Wuhan, Hubei Province, 432000, China. The supplier holds harbor trust tier status with a recorded response rate of 0.00% and zero average response hours on platform-tracked interactions. The company operates in a major Chinese pharmaceutical and chemical manufacturing hub, with proximity to significant research institutions and industrial infrastructure. No founding date, employee count, manufacturing facility details, or regulatory accreditations are stated in the available profile.

The supplier's product focus on protected amino acid derivatives and peptide synthesis intermediates indicates specialisation in fine chemicals for pharmaceutical applications. However, the profile does not distinguish between manufacturing capability and trading/distribution functions. Buyers should verify whether the company holds API manufacturing licences, GMP certification, or ISO 9001/ISO 13485 registration, and whether quality control is performed in-house or through contracted laboratories. The absence of stated client references, audit history, or export licence specifics requires direct verification before pharmaceutical-grade procurement.