Beta-d-ribofuranose 1-acetate 2, 3, 5-trib

Beta-d-ribofuranose 1-acetate 2,3,5-tribenzoate is an acetylated and benzoylated ribose derivative used as a protected carbohydrate intermediate in nucleoside synthesis and pharmaceutical manufacturing. The compound presents as white to yellowish crystalline material with a density of 1.351 g/cm3 and a sharp melting range of 128-130 degrees Celsius, indicating good crystallinity and phase purity suitable for reproducible reactions. Its high boiling point of 620.984 degrees Celsius at standard pressure reflects substantial thermal stability under vacuum distillation or prolonged reflux conditions. The refractive index of 1.61 is consistent with aromatic ester content and confirms structural identity.

This tribenzoate derivative carries protecting groups at the 2-, 3-, and 5-positions of the ribofuranose ring, leaving the anomeric C-1 position as a single acetate ester that can be selectively activated for glycosylation. The benzoate groups provide robust protection against base-catalyzed degradation while remaining removable under standard Zemplen deacylation or methanolic ammonia conditions. Typical purity for pharmaceutical-grade material of this class exceeds 98 percent by HPLC with specific rotation around +120 degrees (c=1, chloroform), though buyers should request a current certificate of analysis. The crystal habit and colour variation from white to pale yellow often correlate with trace oxidation products or residual solvent, so storage under inert atmosphere is recommended beyond the stated 2-8 degrees Celsius.

Primary applications include serving as a glycosyl donor in the synthesis of antiviral nucleosides such as ribavirin analogues, and as a building block in modified RNA and aptamer research. Buyers are typically API manufacturers, custom synthesis houses, and academic research groups in medicinal chemistry. The compound ships as a specialty fine chemical with hazard classifications R36/38 (irritant to eyes and skin) and safety statements S22-S24/25 (do not breathe dust, avoid contact with skin and eyes). Hangzhou Tacon Co., Ltd. lists this material with no stated MOQ or lead time on the platform, so importers should confirm minimum order quantities, bulk packaging options (typically 1 kg to 25 kg drums for this product class), and available documentation including SDS and analytical data.

Hangzhou Tacon Co., Ltd. operates from a business centre address at 2-1214, West Business Center, Dengyun Road N 0518, Hangzhou 310014, Gongshu, China. The supplier carries a 'harbor' trust tier and an 'imported' supplier tier on the platform, with a response rate of 0.00 percent and an average response time of zero hours recorded. These metrics suggest either a newly registered account or limited active engagement with inbound enquiries through this channel. The company maintains a web presence at tacon-china.net, which buyers may use to independently verify product listings and contact details.

The listing provides no statements about manufacturing facility type, GMP certification status, ISO accreditation, years in operation, or specific clientele. No headcount, revenue figures, or production capacity are disclosed. Buyers should therefore conduct direct due diligence: request proof of manufacturing or trading authorisation, ask for reference shipments to comparable buyers, and verify whether analytical capabilities are in-house or subcontracted. The single product entry visible on this listing suggests either a focused catalogue or selective platform presence. Given the zero response rate, prospective importers may need to use the external website or alternative contact methods to secure quotations and technical documentation.