Import 3-Amino-6-Iodopyrazine-2-Carboxylic Acid Methyl — Buy in Bulk from Supplier in China

3-amino-6-iodopyrazine-2-carboxylic acid methyl ester (CAS 1458-16-8) is a methyl-esterified variant of the corresponding free acid, bearing the same pyrazine core with amino, iodo, and methyl carboxylate substituents. The esterification of the carboxylic acid to a methyl ester alters the compound's reactivity profile, rendering it more amenable to certain synthetic transformations where the free acid would interfere. The supplier specifies a purity of 95% or higher, positioning the material for use as a building block in pharmaceutical and agrochemical research. Its molecular formula is C6H6IN3O2, with a molecular weight of 279.04 g/mol, slightly higher than the acid due to the additional methyl group.

The methyl ester functionality offers distinct advantages in multi-step synthesis: it resists decarboxylation under thermal conditions that would degrade the free acid, and it can be selectively hydrolysed to the acid under mild aqueous base when needed. The amino and iodo groups retain their characteristic reactivity, permitting sequential functionalisation. Typical handling requires similar precautions to the free acid, namely protection from light, moisture, and oxidants. The compound is likely supplied as a crystalline solid, though colour and exact physical form should be confirmed with the supplier before ordering, as batch-to-batch variation in appearance is common for iodinated heterocycles.

Primary buyers include medicinal chemistry groups exploring structure-activity relationships around pyrazine scaffolds, agrochemical companies developing crop protection agents, and academic researchers in organic synthesis. The methyl ester is particularly valued in parallel synthesis and combinatorial chemistry where differential protecting group strategies are employed. Trade terms, minimum order quantities, and lead times from Shanghai Hanhong Chemical Co., Ltd. are subject to direct negotiation, as no fixed values appear in the listing. Buyers should request a detailed quotation including packaging specifications, storage recommendations, and accompanying analytical documentation.

Shanghai Hanhong Chemical Co., Ltd. maintains its registered address at Room 207, Zonghe Building, Jiachuan Road, Shanghai 200237, China. The supplier profile indicates an imported tier classification with harbour trust tier status. Notably, the response rate stands at 0.00% with zero average response hours, signalling that prospective buyers may encounter delays or difficulties in obtaining replies through standard platform channels. This communication pattern necessitates proactive outreach via alternative methods.

The company lists both the free acid and methyl ester variants of 3-amino-6-iodopyrazine-2-carboxylic acid, suggesting a focus on halogenated heterocyclic building blocks for the life sciences sector. No manufacturing capacity details, quality certifications, workforce size, or historical operational data are provided in the available profile. Buyers are advised to request company background information, including establishment date, registered capital, and export experience, directly from Shanghai Hanhong Chemical Co., Ltd. to assess reliability and production scale.