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3-amino-6-iodopyrazine-2-carboxylic acid (CAS 875781-48-9) is a heterocyclic pharmaceutical intermediate with the molecular formula C5H4IN3O2. It carries a pyrazine core substituted with amino, iodine, and carboxylic acid functional groups at the 3, 6, and 2 positions respectively. The compound is supplied with a purity of 95% or higher, making it suitable for demanding synthetic applications in drug discovery and development. Its molecular weight of 265.01 g/mol and halogenated structure render it reactive toward palladium-catalysed cross-coupling and nucleophilic substitution protocols common in medicinal chemistry.
The iodine substituent at C-6 provides a handle for Suzuki, Sonogashira, and Heck couplings, while the amino group at C-3 can be acylated, alkylated, or diazotised to access diverse chemical space. The carboxylic acid at C-2 enables amide and ester formation, or decarboxylative transformations. Standard storage requires protection from light and moisture to prevent oxidative degradation of the iodinated ring. Typical packaging(patch) packaging for such intermediates includes amber glass bottles or sealed aluminium-laminate bags with desiccant, though buyers should confirm the exact packaging configuration with Shanghai Hanhong Chemical Co., Ltd. directly.
This intermediate finds primary use in the synthesis of kinase inhibitors, antiviral agents, and other bioactive molecules where the pyrazine scaffold appears in approved drugs. Buyers include pharmaceutical companies running medicinal chemistry programmes, contract research organisations (CROs), and academic laboratories. The compound is traded globally from Shanghai, with Incoterms such as FOB or CIF available subject to negotiation. Minimum order quantities, lead times, and certificates of analysis should be confirmed directly with the supplier, as these are not fixed in the listing data.
| CAS Number | 875781-48-9 |
| Molecular Formula | C5H4IN3O2 |
| Molecular Weight | 265.01 g/mol (typical) |
| Purity | ≥95% (supplier-stated) |
| Chemical Class | Halogenated pyrazine carboxylic acid |
| Functional Groups | Amino (-NH2), Iodo (-I), Carboxylic acid (-COOH) |
| Appearance | Solid, colour to be confirmed with supplier (typical: off-white to pale yellow crystalline powder) |
| Storage Conditions | 2-8°C, protected from light and moisture (standard for iodinated heterocycles) |
| Primary Application | Pharmaceutical intermediate for kinase inhibitors and antiviral synthesis |
| Available Quantities | Bulk supply; confirm MOQ with supplier |
Shanghai Hanhong Chemical Co., Ltd. is located at Room 207, Zonghe Building, Jiachuan Road, Shanghai 200237, China. The supplier operates on an imported tier basis within the marketplace, with a trust tier classified as harbour. The response rate is recorded at 0.00% and the average response time is zero hours, which indicates that direct communication with this supplier may require persistence or alternative contact methods beyond the platform messaging system.
The company supplies fine chemicals and pharmaceutical intermediates to global buyers, with this listing focused on halogenated pyrazine derivatives for research and industrial synthesis. No verified ISO certifications, specific manufacturing capabilities, client references, or years in operation are stated in the available profile data. Buyers should conduct independent due diligence, request a certificate of analysis for each batch, and verify the supplier's quality management system before committing to orders.
3-Amino-6-iodopyrazine-2-carboxylic acid (CAS 875781-48-9) is a high-purity pharmaceutical intermediate used in organic synthesis and drug discovery research. This heterocyclic compound serves as a key building block in the development of bioactive molecules and active pharmaceutical ingredients. Supplied in bulk packaging with configurable purity levels, it is traded globally by pharmaceutical manufacturers, chemical distributors, and research institutions engaged in fine chemical import and export.
| Business Type | Supplier |
| Year Established | Recently Joined |
| Employees | Contact Supplier |
| Annual Revenue | Contact Supplier |
| Main Products | View Products Tab |
| Major Markets | Global |
| Response Time | <4h |
| Response Rate | New Supplier |
Before placing an order for 3-amino-6-iodopyrazine-2-carboxylic acid from Shanghai Hanhong Chemical Co., Ltd., verify the supplier's business registration and export licence through Shanghai's market supervision bureau. Request a current certificate of analysis for an existing batch to assess analytical rigour, and confirm whether the company operates under GMP or ISO 9001 standards. Ask for reference customers in your region, and consider ordering a small sample to evaluate purity and physical form before committing to bulk quantities.
Logistics from Shanghai typically involve sea freight for bulk orders or air freight for urgent smaller quantities. Incoterms such as FOB Shanghai or CIF destination port are standard for Chinese chemical exports, though the supplier's preferred terms must be confirmed directly. Lead times vary with manufacturing schedules and customs clearance, so buyers should request a firm delivery estimate. Payment terms often require advance payment for first orders from non-responsive suppliers, which increases risk, so letter of credit or escrow arrangements should be discussed.
Quality assurance for pharmaceutical intermediates demands incoming inspection upon receipt, including identity confirmation by proton NMR and purity verification by HPLC against the supplier's CoA. Store the material under the recommended conditions immediately upon arrival, and implement a retest protocol if long-term storage is planned. Retain samples from each batch for traceability, and document any discrepancies for supplier quality agreements. Independent third-party inspection in Shanghai before shipment may be warranted for large-value orders given the supplier's low response rate.
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When sourcing 3-Amino-6-Iodopyrazine-2-Carboxylic Acid for your business, securing the right balance of quality and cost is essential. Shanghai Hanhong Chemical Co., Ltd., a verified supplier based in China, offers this product with key specifications including Pharmaceutical / Research Grade, Min. 95% (customizable to 98-99%), and C5H4IN3O2. By purchasing directly from the manufacturer or authorized exporter, buyers can negotiate favorable FOB prices starting at $8001,200./Unit and manage bulk orders with a minimum order quantity (MOQ) of 1 Unit. This product is actively traded under HS Code 2933.59, making it a staple in the Chemicals & Allied Products sector with strong demand from importing countries worldwide.
Importing 3-Amino-6-Iodopyrazine-2- requires careful attention to shipping logistics, customs compliance, and secure payment terms. Shanghai Hanhong Chemical Co., Ltd. offers flexible shipping options such as Full Container Load (FCL) or Less than Container Load (LCL) via sea freight. To ensure a smooth transaction, buyers should verify import duties for HS Code 2933.59 in their destination country. Common payment methods for international B2B transactions include Letter of Credit (L/C), Telegraphic Transfer (T/T), and Documents against Payment (D/P). All transactions and RFQs are facilitated through EximNext, a leading global B2B marketplace designed to make cross-border trade secure and efficient.
Finding trustworthy partners is the foundation of successful importing. The supplier of this 3-Amino-6-Iodopyrazine-2- has been verified on our platform. Whether you are a distributor, wholesaler, or procurement manager, you can request a free quotation, ask for product samples, and finalize your bulk purchase with confidence. EximNext hosts thousands of verified manufacturers and exporters across 200+ countries. Explore similar products in the Chemicals & Allied Products category and connect with top-tier exporters on our comprehensive import export marketplace. Start your sourcing journey today.
Importing 3-Amino-6-Iodopyrazine-2- requires careful attention to shipping logistics, customs compliance, and secure payment terms. Common shipping options include Full Container Load (FCL) or Less than Container Load (LCL) via sea freight. Buyers should verify import duties for HS Code 2933.59 in their destination country. Common payment methods include Letter of Credit (L/C), Telegraphic Transfer (T/T), and Documents against Payment (D/P).
The current listed wholesale price for 3-Amino-6-Iodopyrazine-2-Carboxylic Acid from Shanghai Hanhong Chemical Co., Ltd. is $8001,200./Unit on FOB terms from China. Prices may vary depending on order volume, packaging, and destination. For the most accurate bulk quote, send a direct RFQ to Shanghai Hanhong Chemical Co., Ltd. through EximNext.
The supplier, Shanghai Hanhong Chemical Co., Ltd., has set a Minimum Order Quantity (MOQ) of 1 Unit for 3-Amino-6-Iodopyrazine-2-. For sample requests or smaller trial orders, contact the supplier directly through our platform's inquiry system.
For international shipping and customs clearance, 3-Amino-6-Iodopyrazine-2-Carboxylic Acid is classified under HS Code 2933.59. Buyers should verify their local customs regulations to determine applicable import duties and taxes for this classification.
To import 3-Amino-6-Iodopyrazine-2- from China, negotiate shipping terms (FOB, CIF, or EXW) directly with Shanghai Hanhong Chemical Co., Ltd.. Ensure you have the necessary import licenses for Chemicals & Allied Products products in your destination country.
Yes, Shanghai Hanhong Chemical Co., Ltd. is a verified supplier on EximNext. You can view their complete company profile, business registration details, certifications, and export history before placing a bulk order.
The key specifications for 3-Amino-6-Iodopyrazine-2-Carboxylic Acid supplied by Shanghai Hanhong Chemical Co., Ltd. include Pharmaceutical / Research Grade, Min. 95% (customizable to 98-99%), and C5H4IN3O2. For a complete technical data sheet or Certificate of Analysis (COA), send an inquiry directly to the supplier through EximNext.
Shanghai Hanhong Chemical Co., Ltd. offers 3-Amino-6-Iodopyrazine-2- with standard export packaging. Custom packaging, private labeling, and OEM/ODM options may also be available for large wholesale orders.
3-Amino-6-Iodopyrazine-2- is actively imported by buyers worldwide. Request a destination-specific CIF or CFR quote from Shanghai Hanhong Chemical Co., Ltd. through our platform.
Shanghai Hanhong Chemical Co., Ltd. maintains international quality certifications. These ensure that the 3-Amino-6-Iodopyrazine-2- meets international quality, safety, and regulatory standards required for cross-border trade.
Click "Request Quotation" on this product page, specify your required quantity, preferred shipping terms, and destination country. Shanghai Hanhong Chemical Co., Ltd. will respond with a detailed wholesale quote including FOB pricing, lead time, and payment options.
Common payment methods include Letter of Credit (L/C), Telegraphic Transfer (T/T), Documents against Payment (D/P), and Escrow services. Confirm accepted terms directly with Shanghai Hanhong Chemical Co., Ltd..
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