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Construction & real estate›💡Electronic & Electrical›🍎Food & Beverages›🛋️Home furnishing & supplies›⚗️Industrial goods & chemical›🪨Minerals & metals›📦Miscellaneous›Bicine, systematic name N,N-bis(2-hydroxyethyl)glycine, is a zwitterionic biological buffer with the molecular formula C6H13NO4 and CAS registry 150-25-4. Hubei New Desheng Materials Technology Co., Ltd. supplies this material as a white crystalline powder with stated purity exceeding 99 percent, suitable for in vitro diagnostic reagent formulation, enzymatic reaction buffers, and electrophoresis applications. The compound possesses a pKa of 8.35 at 25 degrees Celsius, placing its effective buffering range between pH 7.6 and 9.0, which aligns with physiological pH conditions and many enzyme optimal activity zones. This listing originates from the Gedian Development Zone in Ezhou, Hubei Province, an industrial cluster with established chemical manufacturing infrastructure.
The white crystalline appearance indicates successful recrystallisation from aqueous or aqueous-organic solvent systems, with low colour and turbidity specifications that are critical for optical diagnostic applications. Bicine belongs to the Good's buffer family, characterised by low membrane permeability, minimal salt effects, and high water solubility (approximately 1 g/mL at 20 degrees Celsius). The supplier notes room temperature storage, consistent with Bicine's chemical stability when protected from moisture and strong oxidising agents. Typical analytical verification for diagnostic-grade Bicine includes titrimetric assay, heavy metals screening, and endotoxin testing, though the specific test panel completed for this lot is not detailed in the source material.
Primary buyers include IVD reagent manufacturers, clinical diagnostic kit producers, and research institutions requiring consistent lot-to-lot buffering performance. The working concentration range of 3 to 100 millimolar cited by the supplier covers most enzymatic and electrophoretic protocols, from DNA separation gels to serum guanase activity assays. Hubei New Desheng states ISO 9001:2008 system operation and SGS accreditation for certain products, though buyers should confirm whether this specific Bicine SKU falls under certified production lines. Packaging, MOQ, and lead time are not provided in the listing and must be confirmed directly with the supplier's sales team.
| Chemical Name | N,N-bis(2-hydroxyethyl)glycine (Bicine) |
| CAS Number | 150-25-4 (source data) |
| Molecular Formula | C6H13NO4 (source data) |
| Purity | >99% (supplier stated) |
| Appearance | White crystal powder (source data) |
| Typical pKa (25°C) | 8.35 +/- 0.02 (standard literature value) |
| Typical Effective Buffering Range | pH 7.6 - 9.0 (standard for Bicine) |
| Typical Working Concentration | 3-100 mM (supplier stated; typical for enzymatic and electrophoretic applications) |
| Typical Solubility in Water | >1 g/mL at 20°C (standard) |
| Typical Heavy Metals Limit | <5 ppm as Pb (standard specification for reagent grade; confirm with supplier) |
| Storage Condition | Room temperature (supplier stated; protect from moisture) |
Hubei New Desheng Materials Technology Co., Ltd. operates from 8-2-2, Union Technology Area C, Gedian Development Zone, Ezhou, Hubei Province, China, postal code 436070. The company traces its origins to Wuhan Desheng Chemical Technology Company, established in April 2005, and positions itself as a specialist in in vitro diagnostic chemical reagents. The listing indicates ISO 9001:2008 quality management system operation and partial SGS product certification, though the scope of SGS coverage is unspecified. The supplier reports that 50% of staff hold bachelor degrees, 20% master degrees, and all research and development personnel are masters, figures that should be treated as self-reported and unverified.
The company's product portfolio extends beyond Bicine to blood collection tube additives, diagnostic kit raw materials, and enhanced chemiluminescent reagents. Domestic clientele includes recognised medical device firms such as Improve Medical in Guangdong, Zhejiang Gongdong, and Zhejiang K.S. Medical, suggesting established supply relationships within China's IVD supply chain. Export activity is claimed across 28 countries, though no specific markets or distribution partners are named. The response rate shows zero percent with zero average response hours, indicating either a legacy listing, inactive enquiry management, or data collection artefact. Buyers should verify current operational status and export licence validity for chemical reagents before placing orders.
| 企业类型 | Supplier |
| 成立年份 | Contact Supplier |
| Employees | Contact Supplier |
| Annual Revenue | Contact Supplier |
| Main Products | View Products Tab |
| Major Markets | Global |
| 响应时间 | <4h |
| 响应率 | Contact Supplier |
Before ordering Bicine from Hubei New Desheng Materials Technology Co., Ltd., verify that the legal entity named on the proforma invoice matches the supplier profile, and that export documentation for chemical substances is current under Chinese customs regulations. Request a current business licence, export licence for chemical reagents, and ISO 9001:2008 certificate with scope explicitly covering Bicine or biological buffer manufacturing. Validate the claimed domestic client references (Improve Medical, Zhejiang Gongdong, Zhejiang K.S. Medical) through independent channels where possible, as reference verification reduces supplier misrepresentation risk. Given the zero response rate displayed, initiate contact through multiple channels (email, telephone, WeChat) to confirm active account management.
Logistics for chemical reagent export from Hubei Province typically routes through Wuhan Tianhe International Airport for air freight, or via Shanghai/Ningbo sea ports for ocean freight. Bicine is not classified as dangerous goods under UN regulations, though material safety data sheet provision is mandatory for international chemical shipments. Confirm with the supplier whether they provide MSDS in your destination language, and whether Incoterms offered include EXW Ezhou, FOB Shanghai/Ningbo, CIF destination, or DAP terms. For temperature-sensitive or humidity-sensitive materials, specify climate-controlled container or insulated packaging with temperature logger. Payment terms for initial orders should utilise secure methods; consider 30% advance with 70% against copy of bill of lading, or documentary collection through a bank with presence in both jurisdictions.
Quality assurance on receipt requires visual inspection for colour change (yellowing indicates degradation), caking (moisture ingress), and foreign particle contamination. Prepare test solutions at 25 mM and 50 mM nominal concentration, measure pH at 25 degrees Celsius (expected 8.3 to 8.4 for 25 mM), and compare to certificate of analysis values. Retain a representative sample from each delivery lot in original packaging, stored under identical conditions to the bulk, for dispute resolution or investigation of downstream assay failures. Documentation to archive includes certificate of analysis, certificate of origin, packing list, commercial invoice, and batch-specific stability data. Establish a vendor qualification protocol with defined acceptance criteria for future deliveries to ensure consistent IVD reagent supply chain performance.
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