从China供应商批发进口3-Bromo-5-Hydroxypyridine — FOB条款

3-Bromo-5-hydroxypyridine (CAS 74115-13-2) is a brominated heterocyclic intermediate with molecular formula C5H4BrNO and molecular weight of 173.99 g/mol, appearing as an off-white to pale yellow crystalline powder. This compound features a pyridine ring substituted at the 3-position with bromine and at the 5-position with hydroxyl, conferring dual reactivity sites for nucleophilic substitution and metal-catalysed cross-coupling. Tomson Chemical Co, .Ltd, located in Hangzhou, Zhejiang Province, lists this material for bulk export in industrial purity grades, with the bromo-hydroxypyridine structure making it particularly suited to pharmaceutical and agrochemical synthesis pathways.

The material is typically manufactured to a purity specification of 98% minimum by HPLC, with standard pharmaceutical intermediates often requiring residual solvent limits conforming to ICH Q3C guidelines. Moisture content is typically controlled below 0.5% by Karl Fischer titration to prevent hydrolysis of the bromine substituent during extended storage. The melting point range for this compound is typically 210-215 degrees Celsius with decomposition, though buyers should request a batch-specific Certificate of Analysis to confirm individual lot parameters. Packaging for such halogenated heterocycles is standard in lined fibre drums or UN-certified plastic containers with desiccant, typically 25 kg net weight, to preserve stability during international shipment from Chinese chemical manufacturing zones.

Primary applications include use as a building block for kinase inhibitors, antiviral agents, and fungicidal active ingredients where the pyridine scaffold provides metal-chelation or hydrogen-bonding functionality. Research laboratories and contract manufacturing organisations utilise this intermediate in Suzuki, Stille, and Buchwald-Hartwig coupling sequences. Buyers should confirm with Tomson Chemical whether the material is supplied as a standard catalogue item or manufactured on demand, as lead times for brominated pyridines can vary significantly based on bromination step scheduling and environmental compliance batch releases at the Zhejiang facility.

Tomson Chemical Co, .Ltd operates from premises at 120c 12f Chaohui Road 308 in Hangzhou, Zhejiang Province, 310000, China, placing it within one of the country's densest concentrations of fine chemical and pharmaceutical intermediate manufacturers. The supplier holds a Harbor trust tier designation on the platform, indicating a baseline verification level, though its response rate is recorded at 0.00% with zero average response hours, suggesting limited or no engagement through the platform messaging system. Buyers should therefore anticipate that initial contact and ongoing communication may require direct outreach to the Chaohui Road address or established chemical industry channels rather than platform-mediated enquiry.

The listing presents Tomson Chemical as a bulk supplier of 3-bromo-5-hydroxypyridine for global export, with the product categorised under organic heterocyclic compounds. Notably, the supplier profile does not disclose manufacturing capacity, reactor scale, GMP certification status, whether the facility operates under ISO management systems, or any specific export licence details. The absence of stated client references, annual turnover, or employee count means buyers must conduct independent due diligence on manufacturing credentials, environmental compliance permits, and quality management systems before committing to pharmaceutical-grade supply agreements.