Import Boc-His — Buy in Bulk from Supplier in China

Boc-his from Chengdu Cp Biochem Co., Ltd refers to N-alpha-tert-butoxycarbonyl-L-histidine or a related protected histidine derivative, a fundamental building block in peptide synthesis supplied from the Hi-Tech Zone in Chengdu, Sichuan Province, China. The source description references a tosylated variant, Boc-his(tos)-OH, indicating side-chain protection of the imidazole nitrogen with a tosyl group, though buyers should confirm the exact product form as the listing uses both generic and specific nomenclature. The supplier claims purity exceeding 99% for this material, positioning it within the standard range for research-grade and GMP-starting material peptide reagents. Chengdu Cp Biochem operates from the D-11, Flat A, Building 1# address in Chengdu's Hi-Tech Zone, a cluster for biotech and pharmaceutical R&D in western China.

The Boc protecting group on the alpha-amino function is standard for solution-phase and some solid-phase peptide synthesis protocols, cleavable with TFA while remaining stable to mild base conditions. Histidine presents particular synthetic challenges due to the imidazole side chain, which is nucleophilic and can participate in unwanted acyl transfer or racemisation; tosyl or similarly bulky protection mitigates this. The material is described as stable under varied conditions, though specific temperature, light sensitivity, and moisture stability parameters are not quantified. Typical industry packaging for such reagents includes amber glass bottles with inert atmosphere or vacuum sealing, often in sizes from gram to multi-kilogram quantities, with argon or nitrogen headspace to prevent oxidation of the sensitive imidazole ring.

Applications span pharmaceutical peptide manufacturing, including therapeutic peptide hormones, diagnostic peptide probes, and vaccine epitope synthesis. The compound serves academic laboratories developing metal-coordinating peptides or enzyme mimics exploiting histidine's imidazole chemistry. Buyers should confirm whether the specific product is the free acid, ester, or another variant, and whether the tosyl group is on N-imidazole-1 or N-imidazole-3 (tele), as this affects deprotection strategy and peptide coupling efficiency. The supplier's imported tier status indicates platform recognition, though the zero response rate means direct communication testing is essential before reliance. Sichuan's logistics infrastructure connects through Chengdu Shuangliu International Airport and the Chengdu-Europe railway for continental freight.

Chengdu Cp Biochem Co., Ltd is located at D-11, Flat A, Building 1#, Hi-Tech Chengdu, Sichuan Province, China, postal code 610041, placing it within the Chengdu Hi-Tech West Zone, a major hub for biotechnology and pharmaceutical development in western China. The supplier holds an imported tier and harbor trust tier designation on the platform, with a recorded response rate of 0.00% and no average response hour data, indicating an absence of historical quote response metrics. The company name suggests specialisation in biochemical products, though the profile does not detail manufacturing scope, in-house synthesis versus trading operations, or facility accreditations. No ISO, GMP, or other certification claims are made in the available data.

The listing emphasises purity and stability without providing batch-specific analytical support or manufacturing details. Buyers should note that the source description contains unverified claims about ISO and SGS certifications that do not originate from supplier-submitted data and should be disregarded, requesting direct documentation instead. The flat/office address format rather than industrial park designation may indicate trading or small-scale operations rather than large-scale manufacturing. Prospective buyers should conduct due diligence on the company's registration with the Chengdu Market Supervision Administration and request evidence of chemical handling licences.