Import Betulinic Acid — Buy in Bulk from Supplier in China

Betulinic acid (CAS 472-15-1, molecular formula C30H48O3, molecular weight 456.7 g/mol) is a pentacyclic trialkyl triterpenoid compound extracted primarily from birch bark, with this offering from Hebei Tianao Technology Co., Ltd sourced from China. The compound exhibits a melting point of 295-298 °C (decomposition, literature value) and a specific optical rotation of [α]D25 +7.5° (c = 0.37 in pyridine), with a predicted density of 1.065 ± 0.06 g/cm³ and predicted boiling point of 550.0 ± 33.0 °C. Storage requires refrigeration at +4 °C to maintain stability of the powder.

The product is isolated through extraction and purification from birch bark (Betula species), the standard industrial source that has superseded earlier isolation from Rhamnaceae species native to Eastern Africa. The pentacyclic structure confers characteristic lipophilicity, with solubility in organic solvents such as pyridine, chloroform, and ethanol, but negligible aqueous solubility without formulation enhancement. Typical commercial grades range from 95% to 98% purity by HPLC, though the supplier's exact assay should be confirmed. The refractive index measurement of 7.8 ° (C = 0.9, pyridine) serves as an identity confirmation parameter in pharmacopoeial testing.

Pharmaceutical and cosmetic manufacturers constitute the primary buyers, utilizing betulinic acid in anti-cancer drug research, anti-inflammatory formulation development, and dermatological applications including anti-aging and moisturizing products. Research institutions and biotechnology companies also procure this compound for mechanism-of-action studies and novel drug delivery system development. Import buyers should verify the supplier's batch-specific certificate of analysis, confirm EINECS compliance (207-448-8), and establish whether the material is intended for research, pharmaceutical, or cosmetic grade use, as specification requirements differ markedly across these applications.

Hebei Tianao Technology Co., Ltd is a China-based supplier listed as an imported-tier vendor with harbor-level trust verification. The supplier profile indicates zero response rate and zero average response hours, which suggests either a newly registered account or inactive inquiry management. Buyers should note this communication gap and consider direct contact methods beyond platform messaging to establish procurement channels.

The listing provides chemical and physical data for betulinic acid but does not disclose manufacturing capacity, GMP certification status, analytical capabilities, or quality management system accreditation. No information is given about batch sizes, custom synthesis services, or regulatory documentation beyond the EINECS reference. The supplier's location in Hebei Province, a major chemical manufacturing region in China, offers logistical advantages for bulk shipment through Tianjin Port, though buyers must independently verify production facility audits and compliance with IPEC or USP excipient guidelines if pharmaceutical use is intended.