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5-bromophthalide (CAS 64169-67-5) is a brominated phthalide derivative with molecular formula C8H5BrO2 and molecular weight 233.03 g/mol. Hebei Hua-chem Group supplies this compound as a white to off-white crystalline powder with demonstrated solubility in organic solvents and stability under standard storage conditions. The brominated aromatic lactone structure positions this material as a reactive intermediate for downstream synthesis rather than a finished active ingredient.
The material is typically manufactured via bromination of phthalide or related ring-closure routes, with standard commercial grades targeting purity levels suitable for pharmaceutical and agrochemical intermediate applications. Typical specifications for this compound class include melting point ranges, HPLC purity minima, and specified limits for related substances and residual solvents. Standard packaging for such specialty brominated intermediates ranges from 25 kg fibre drums to 200 kg steel drums, depending on order volume and customer requirements, with moisture barrier liners to protect hygroscopic properties.
Primary buyers include pharmaceutical API manufacturers, agrochemical formulators, and specialty dye producers who require brominated building blocks for C-N and C-C coupling reactions. The compound serves as a precursor to phthalide-based bioactive molecules and fluorescent materials. For procurement from Hebei Hua-chem Group, buyers should confirm minimum order quantities, available packaging formats, and whether the material is supplied from stock or manufactured to order. The supplier's location in Dongguang County, Hebei Province, offers access to Tianjin Port for international shipment.
| Molecular Formula | C8H5BrO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | White to off-white crystalline powder (typical for commercial grade) |
| Solubility | Soluble in organic solvents (source-confirmed); insoluble in water (typical) |
| Melting Point | 150-155 °C (typical range for standard purity grade) |
| Assay (HPLC) | ≥98.0% (standard commercial specification; confirm certificate of analysis) |
| Loss on Drying | ≤0.5% (typical specification for crystalline intermediates) |
| Residual Solvents | Per ICH Q3C limits (standard pharmaceutical intermediate requirement) |
| Standard Packaging | 25 kg fibre drum with PE liner, or 200 kg steel drum (typical options; confirm with supplier) |
| Storage Conditions | Store in tightly closed container, protected from moisture and light, at 2-8 °C (standard for brominated lactone intermediates) |
Hebei Hua-chem Group is located in Dongguang County, Hebei Province, with the address South Of Dongguang County, Dongguang 061600, China. The supplier is classified at the imported tier with a harbor trust designation, indicating basic platform verification without advanced assurance credentials. The response rate is recorded at 0.00% with zero average response hours, which buyers should interpret as an absence of engagement data rather than a negative signal. No ISO, GMP, or other certification claims are present in the supplier profile.
The listing does not disclose manufacturing capacity, R&D infrastructure, export licence details, or specific quality management systems. Hebei Province is a significant concentration zone for China's chemical and pharmaceutical intermediate industry, with established logistics corridors to Tianjin and Qingdao ports. Buyers are advised to conduct direct due diligence on production capabilities, environmental compliance status, and batch-to-batch consistency protocols before committing to volume orders.
| Business Type | Supplier |
| Year Established | Recently Joined |
| Employees | Contact Supplier |
| Annual Revenue | Contact Supplier |
| Main Products | View Products Tab |
| Major Markets | Global |
| Response Time | <4h |
| Response Rate | New Supplier |
Before placing an order with Hebei Hua-chem Group, verify the supplier's business licence, export rights, and environmental compliance permits for brominated compound manufacture. Request a current CoA from a recent production batch and cross-check analytical methods against your internal specifications. Confirm that the supplier can provide regulatory documentation for your destination country, as brominated aromatic intermediates face increasing scrutiny under REACH, TSCA, and analogous frameworks.
Logistics planning should account for Hebei Province's inland location, approximately 200 km from Tianjin Port. Clarify Incoterms (EXW, FOB Tianjin, or CIF destination are common for this trade lane), freight forwarder relationships, and whether the supplier has experience with IMO-classified cargo if the material meets hazardous goods criteria. Payment terms typical for first transactions with Chinese chemical suppliers are 30% TT advance with 70% against copy of B/L, though L/C at sight may be negotiable for larger volumes. Confirm currency, banking charges, and any export licence requirements under China's chemical export regulations.
Upon receipt, conduct independent identity verification by FT-IR or NMR against a reference standard, and quantification by HPLC with appropriate internal standard. Test for residual brominating agents and solvent traces if not covered by supplier CoA. For pharmaceutical applications, consider third-party audit of the manufacturing facility against ICH Q7 GMP for APIs or appropriate intermediate GMP standards. Retain samples from each batch for stability monitoring and comparative analysis should quality deviations arise in downstream processing.
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Securing a reliable supply chain for 5-Bromophthalide is critical for maintaining your business operations. Hebei Hua-chem Group, a verified supplier located in China, provides high-quality 5-Bromophthalide ready for international export. By connecting directly with this supplier, buyers can bypass intermediaries, negotiate custom wholesale pricing, and arrange bulk shipments. This product is a key offering within the Products industry, catering to distributors, wholesalers, and importers worldwide.
Navigating the complexities of global sourcing is easier when you have direct access to the right manufacturers and exporters. When importing 5-Bromophthalide from China, buyers can discuss shipping logistics, packaging requirements, and preferred payment terms directly with Hebei Hua-chem Group. This seamless communication is powered by EximNext, a premier global B2B marketplace that connects ambitious buyers with verified global sellers across every major industry.
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When importing 5-Bromophthalide from China, buyers should consider shipping terms (FOB, CIF, EXW), customs documentation requirements, and payment security. Contact the supplier to discuss the best logistics options for your destination country.
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