4-Bromoindole

4-Bromoindole is a halogenated nitrogen heterocycle with molecular formula C8H6BrN and CAS 52488-36-5, valued in medicinal chemistry for its use as a scaffold in kinase inhibitor and serotonin receptor ligand programmes. The compound consists of a bromine substituent at the 4-position of the indole bicyclic system, a placement that directs subsequent metal-catalysed functionalisation toward the 2- and 7-positions with useful regioselectivity. Yixing Zhongyu Medicine Technology Co., Ltd. supplies this material from Jingtang Industrial Park in Yixing, Jiangsu Province, China, with the source data indicating minimum purity of 98% by unstated analytical method.

The indole nitrogen (pKa approximately 16.2 in DMSO) renders the compound mildly acidic, forming salts with strong bases and participating in N-alkylation under basic conditions. Typical industrial specifications for 4-bromoindole include a melting point range of 65-68 degrees C and a molecular weight of 196.05 g/mol. Standard quality parameters beyond assay include HPLC purity at 254 nm, residual solvent content by GC-HS, and heavy metal limits. The compound is light-sensitive and typically supplied in amber containers with inert atmosphere headspace. Packaging configurations from Chinese suppliers commonly range from gram-scale amber vials to kilogram-scale fluoropolymer-lined drums, though exact options require direct confirmation with Yixing Zhongyu.

Primary demand for 4-bromoindole originates from pharmaceutical contract research organisations and biotechnology companies developing targeted therapeutics, where the bromine handle enables rapid analogue synthesis via Suzuki, Stille, or Negishi couplings. Academic research groups in synthetic methodology also represent a significant buyer segment. Trade execution from this Jiangsu-based supplier would typically ship through Shanghai or Ningbo port, with Incoterms to be negotiated directly given that the profile does not specify standard terms. The supplier's trust tier is harbour with zero recorded response metrics, necessitating proactive engagement to confirm availability, exact MOQ, and current batch specifications before purchase commitment.

Yixing Zhongyu Medicine Technology Co., Ltd. is located in Jingtang Industrial Park, Yixing 214244, China, placing it within the Yangtze River Delta chemical manufacturing corridor with established infrastructure for pharmaceutical and fine chemical production. The company is classified under supplier tier imported and trust tier harbour, with both response rate and average response hours recorded at zero in the available data. This profile characteristic suggests either limited platform transaction history or a recently established listing, and buyers should not assume operational scale or export experience from these indicators alone.

The supplier profile does not disclose founding date, employee count, annual turnover, GMP or ISO certifications, or specific manufacturing equipment. Their product positioning emphasises pharmaceutical and chemical synthesis materials, with 4-bromoindole representing a halogenated indole in what may be a broader heterocyclic compound catalogue. Given the absence of documented verification signals, direct due diligence is essential: request facility audit reports, confirm whether synthesis is performed in-house or through toll manufacturing partners, and ask for regulatory starting material documentation if the application requires pharmacopoeial compliance. Verify their experience with temperature-controlled shipping and their capability to provide batch-specific analytical data packages including HNMR, C13 NMR, and HPLC chromatograms with peak integration parameters.