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3-Bromo-2,3,4,5-tetrahydro-2-OXO-1H-1-benzazepin is a brominated benzazepine derivative with CAS number 86499-96-9. The compound from Ningbo Samreal Chemical Co., Ltd. is supplied as a white or white crystalline powder with an assay purity of 99.0 percent. It is slightly soluble in ethanol, benzene, and acetone, and insoluble in water. This heterocyclic ketone contains a seven-membered azepine ring fused to a benzene ring, with a bromine substituent at the 3-position and a carbonyl at the 2-position, making it a useful scaffold for medicinal chemistry.
The 99.0 percent assay specification is typical for intermediate-grade pharmaceutical chemicals, though buyers should clarify whether this figure refers to area percent by HPLC, weight percent by titration, or another analytical method. The crystalline form suggests a defined melting point range, which buyers should request to verify batch consistency. Solubility in polar aprotic solvents such as acetone and benzene, combined with water insolubility, is characteristic of this molecular class and influences formulation and reaction design. The bromine substituent provides a handle for further metal-catalyzed coupling reactions, a common application in pharmaceutical synthesis.
This compound serves as a synthetic intermediate for laboratories and chemical manufacturing companies developing benzazepine-based pharmaceuticals, including potential candidates for neurological and cardiovascular targets. Buyers include custom synthesis houses, contract research organizations, and generic API manufacturers. Packaging format, MOQ, lead time, and specific quality documentation are not stated in the source and must be confirmed with Ningbo Samreal Chemical Co., Ltd. directly. The compound requires standard handling precautions for brominated organics, including avoidance of dust inhalation and contact with strong bases or oxidizers.
| CAS Number | 86499-96-9 |
| Chemical Name | 3-Bromo-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin |
| Assay Purity | 99.0% (buyer should confirm analytical method: HPLC, GC, or titration) |
| Physical Appearance | White or white crystalline powder |
| Solubility Ethanol | Slightly soluble (typical for brominated benzazepine derivatives of this molecular weight range) |
| Solubility Benzene | Slightly soluble |
| Solubility Acetone | Slightly soluble |
| Solubility Water | Insoluble |
| Molecular Formula | C10H10BrNO (calculated from systematic name; buyer should request confirmed formula and molecular weight from supplier) |
| Typical Use | Pharmaceutical intermediate for benzazepine synthesis (standard application for halogenated heterocyclic ketones) |
Ningbo Samreal Chemical Co., Ltd is located at Room 1007, No.1498 Jiangnan Road, Hi-Tech Zone, Ningbo, Zhejiang Province, China, postal code 315040. The supplier tier is imported and the trust tier is harbor, with a response rate of 0.00 percent and zero average response hours, indicating no response data is available. No information about year of establishment, number of employees, annual revenue, production capacity, or registered capital is provided in the source profile.
The address places the supplier in Ningbo's high-technology district, an area with concentration of chemical trading and specialty chemical companies. No factory location, manufacturing license number, or quality certifications are stated in the available data. Buyers should verify the company's business license, any chemical production or trading permits, and whether the company operates as a manufacturer, a trader, or both. Direct communication with the supplier is essential to confirm these details before entering into supply agreements for pharmaceutical intermediates.
| Business Type | Supplier |
| Year Established | Recently Joined |
| Employees | Contact Supplier |
| Annual Revenue | Contact Supplier |
| Main Products | View Products Tab |
| Major Markets | Global |
| Response Time | <4h |
| Response Rate | New Supplier |
Before ordering, verify that Ningbo Samreal Chemical Co., Ltd. holds a valid chemical business license and any special permits for manufacturing or trading pharmaceutical intermediates. Request the company's ISO certification status, though none is confirmed in the source, and ask for a quality agreement that defines batch release criteria, deviation handling, and change control procedures. Confirm the compound's regulatory status in your destination country, including whether it requires import notification to environmental or drug control agencies. For pharmaceutical applications, assess whether the supplier's quality system meets GMP or GMP-like standards for intermediates, and whether they can support regulatory filings with complete documentation packages including starting material traceability and impurity characterization.
Shipments from Ningbo typically depart via Shanghai or Ningbo port for sea freight, or Shanghai Pudong for air freight. Confirm Incoterms with the supplier, whether EXW Ningbo, FOB Shanghai, or CIF destination, and clarify who arranges hazardous materials documentation if the compound is classified as dangerous goods. The compound contains bromine and may fall under UN classification depending on concentration and form, affecting packaging, labeling, and carrier acceptance. Request the material safety data sheet, transport classification, and any required dangerous goods declarations. Payment terms should be negotiated with care for first orders, with documentary credit or secure escrow preferred over open account until the relationship is established. Lead times and MOQ are not stated and must be confirmed directly with the supplier.
On receipt, inspect packaging for integrity, checking for punctures, moisture ingress, or temperature excursion indicators if shipped under controlled conditions. Verify that the batch number, manufacture date, and retest date on the label match the certificate of analysis. Perform identity testing by IR or NMR comparison to a reference standard, and assay verification by your validated method before release to production. Retain samples under quarantine until testing is complete. Document any discrepancies immediately and notify the supplier within the contractual claim period. For ongoing supply, consider establishing a vendor qualification program with annual audits, periodic full analytical testing, and monitoring ofsupplier response and delivery performance. Establish specifications for critical quality attributes including purity, impurities, residual solvents, and physical properties to ensure batch-to-batch consistency for your applications.
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When importing 3-Bromo-2,3,4,5-Tetrahydr from China, buyers should consider shipping terms (FOB, CIF, EXW), customs documentation requirements, and payment security. Contact the supplier to discuss the best logistics options for your destination country.
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Yes, Ningbo Samreal Chemical Co., Ltd provides 3-Bromo-2,3,4,5-Tetrahydr for bulk export from China. You can negotiate the MOQ, packaging details, and shipping terms directly with the supplier.
Shipping terms such as FOB, CIF, or EXW can be negotiated directly with Ningbo Samreal Chemical Co., Ltd. Contact the supplier to discuss the best logistics options for importing 3-Bromo-2,3,4,5-Tetrahydr to your country.
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