Import 3, 4, 5-Trifluorobenzoic Acid — Buy in Bulk from Supplier in China

3,4,5-Trifluorobenzoic acid (CAS 121602-93-5, molecular formula C7H2F3O2) is a fluorinated aromatic carboxylic acid widely employed as a building block in advanced pharmaceutical and agrochemical synthesis. Chang Zhou Qi Di Chemical Co., Ltd. offers this material at a purity of 99% or higher, a threshold suitable for most medicinal-chemistry and scale-up applications where fluorine substitution modulates metabolic stability and lipophilicity. The compound's three fluorine atoms in the 3,4,5-positions create distinct electronic properties that direct subsequent electrophilic substitution patterns, making it valuable for SAR studies and route development.

The 99% purity specification typically refers to area-% purity by GC or HPLC, though buyers should confirm the exact analytical method and whether the figure represents assay (titrimetric) or chromatographic purity. Standard synthesis routes involve diazotisation-fluorination of aminobenzoic acids or halogen-exchange chemistry, with residual impurities potentially including positional isomers (2,3,4- or 2,4,5-trifluorobenzoic acid), difluorobenzoic acids, and traces of heavy-metal catalysts from cross-coupling steps. Jiangsu province, where Changzhou is located, hosts a dense cluster of fluorochemical manufacturers with access to anhydrous hydrogen fluoride and specialised fluorination equipment.

Primary end-users include pharmaceutical companies developing kinase inhibitors, antibiotics, and CNS-active compounds, agrochemical formulators synthesising fungicides and herbicides with fluorinated phenyl cores, and dye manufacturers seeking colour-fast intermediates. The acid functions as a protected carboxylic acid for amide and ester formation, or as a precursor to 3,4,5-trifluorophenyl derivatives via decarboxylative protocols. Buyers must confirm packaging specifications (typical: 25 kg fibre drums or fluoropolymer-lined pails), storage recommendations (cool, dry, well-ventilated to prevent sublimation and moisture uptake), and exact trade terms with Chang Zhou Qi Di Chemical Co., Ltd., as these operational details are absent from the source material.

Chang Zhou Qi Di Chemical Co., Ltd. is located at 128-1-16 Huayuan Street, Hutang Town, Wujin District, Changzhou 213161, Jiangsu, China. The supplier carries an imported tier and harbor trust classification on the platform. The response rate is 0.00% with zero average response hours recorded, indicating no tracked inquiry history. Buyers should independently verify operational status, export credentials, and technical competence through direct engagement, reference checks, or third-party verification services before committing to purchase.

The company operates within Changzhou's established chemical-industry corridor in Jiangsu province, a region with significant fluorochemical manufacturing infrastructure. The source description does not specify production scale, reactor types (glass-lined, Hastelloy for HF handling), in-house analytical capabilities, environmental compliance records, or R&D staffing. No certifications, client lists, revenue figures, years in operation, or factory-visit policies are provided. Buyers should request current ISO certificates, safety-data-sheet authoring compliance, and evidence of hazardous-chemicals export licence coverage for fluorinated organics.